In-vitro derived germinal centre B cells differentially generate memory B or plasma cells in vivo
نویسندگان
چکیده
منابع مشابه
Early appearance of germinal center–derived memory B cells and plasma cells in blood after primary immunization
Immunization with a T cell-dependent antigen elicits production of specific memory B cells and antibody-secreting cells (ASCs). The kinetic and developmental relationships between these populations and the phenotypic forms they and their precursors may take remain unclear. Therefore, we examined the early stages of a primary immune response, focusing on the appearance of antigen-specific B cell...
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ژورنال
عنوان ژورنال: Nature Communications
سال: 2011
ISSN: 2041-1723
DOI: 10.1038/ncomms1475